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Identification of the Endogenous Key Substrates of the Human Organic Cation Transporter OCT2 and Their Implication in Function of Dopaminergic Neurons

BACKGROUND: The etiology of neurodegenerative disorders, such as the accelerated loss of dopaminergic neurons in Parkinson's disease, is unclear. Current hypotheses suggest an abnormal function of the neuronal sodium-dependent dopamine transporter DAT to contribute to cell death in the dopamine...

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Detalhes bibliográficos
Main Authors: Taubert, Dirk, Grimberg, Gundula, Stenzel, Werner, Schömig, Edgar
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851987/
https://ncbi.nlm.nih.gov/pubmed/17460754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000385
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