The Class I Histone Deacetylase Inhibitor MS-275 Prevents Pancreatic Beta Cell Death Induced by Palmitate

Elevation of the dietary saturated fatty acid palmitate contributes to the reduction of functional beta cell mass in the pathogenesis of type 2 diabetes. The diabetogenic effect of palmitate is achieved by increasing beta cell death through induction of the endoplasmic reticulum (ER) stress markers...

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Detalhes bibliográficos
Publicado no:J Diabetes Res
Main Authors: Plaisance, Valérie, Rolland, Laure, Gmyr, Valéry, Annicotte, Jean-Sébastien, Kerr-Conte, Julie, Pattou, François, Abderrahmani, Amar
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294305/
https://ncbi.nlm.nih.gov/pubmed/25610877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/195739
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