The Class I Histone Deacetylase Inhibitor MS-275 Prevents Pancreatic Beta Cell Death Induced by Palmitate

Elevation of the dietary saturated fatty acid palmitate contributes to the reduction of functional beta cell mass in the pathogenesis of type 2 diabetes. The diabetogenic effect of palmitate is achieved by increasing beta cell death through induction of the endoplasmic reticulum (ER) stress markers...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Diabetes Res
Egile Nagusiak: Plaisance, Valérie, Rolland, Laure, Gmyr, Valéry, Annicotte, Jean-Sébastien, Kerr-Conte, Julie, Pattou, François, Abderrahmani, Amar
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Hindawi Publishing Corporation 2014
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294305/
https://ncbi.nlm.nih.gov/pubmed/25610877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/195739
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