bis-Molybdopterin Guanine Dinucleotide Is Required for Persistence of Mycobacterium tuberculosis in Guinea Pigs

Mycobacterium tuberculosis is able to synthesize molybdopterin cofactor (MoCo), which is utilized by numerous enzymes that catalyze redox reactions in carbon, nitrogen, and sulfur metabolism. In bacteria, MoCo is further modified through the activity of a guanylyltransferase, MobA, which converts Mo...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Williams, Monique J., Shanley, Crystal A., Zilavy, Andrew, Peixoto, Blas, Manca, Claudia, Kaplan, Gilla, Orme, Ian M., Mizrahi, Valerie, Kana, Bavesh D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Bacterial Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294236/
https://ncbi.nlm.nih.gov/pubmed/25404027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02722-14
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