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Intratumoral anti-HuD immunotoxin therapy for small cell lung cancer and neuroblastoma

BACKGROUND: Most patients with small cell lung cancer (SCLC) or neuroblastoma (NB) already show clinically detectable metastases at diagnosis and have an extremely poor prognosis even when treated with combined modalities. The HuD-antigen is a neuronal RNA-binding protein that is expressed in 100% o...

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Detalhes bibliográficos
Publicado no:J Hematol Oncol
Main Authors: Ehrlich, Debra, Wang, Bo, Lu, Wei, Dowling, Peter, Yuan, Ruirong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4293823/
https://ncbi.nlm.nih.gov/pubmed/25523825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-014-0091-3
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