Patients with lung cancer and paraneoplastic Hu syndrome harbor HuD-specific type 2 CD8(+) T cells

Paraneoplastic neurologic disorders (PNDs) offer an uncommon opportunity to study human tumor immunity and autoimmunity. In small cell lung cancer (SCLC), expression of the HuD neuronal antigen is thought to lead to immune recognition, suppression of tumor growth, and, in a subset of patients, trigg...

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Hlavní autoři: Roberts, Wendy K., Deluca, Ilana J., Thomas, Ashby, Fak, John, Williams, Travis, Buckley, Noreen, Dousmanis, Athanasios G., Posner, Jerome B., Darnell, Robert B.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2009
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701858/
https://ncbi.nlm.nih.gov/pubmed/19509467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI36131
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