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Patients with lung cancer and paraneoplastic Hu syndrome harbor HuD-specific type 2 CD8(+) T cells

Paraneoplastic neurologic disorders (PNDs) offer an uncommon opportunity to study human tumor immunity and autoimmunity. In small cell lung cancer (SCLC), expression of the HuD neuronal antigen is thought to lead to immune recognition, suppression of tumor growth, and, in a subset of patients, trigg...

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書誌詳細
主要な著者: Roberts, Wendy K., Deluca, Ilana J., Thomas, Ashby, Fak, John, Williams, Travis, Buckley, Noreen, Dousmanis, Athanasios G., Posner, Jerome B., Darnell, Robert B.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701858/
https://ncbi.nlm.nih.gov/pubmed/19509467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI36131
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