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Intratumoral anti-HuD immunotoxin therapy for small cell lung cancer and neuroblastoma

BACKGROUND: Most patients with small cell lung cancer (SCLC) or neuroblastoma (NB) already show clinically detectable metastases at diagnosis and have an extremely poor prognosis even when treated with combined modalities. The HuD-antigen is a neuronal RNA-binding protein that is expressed in 100% o...

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Pubblicato in:J Hematol Oncol
Autori principali: Ehrlich, Debra, Wang, Bo, Lu, Wei, Dowling, Peter, Yuan, Ruirong
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4293823/
https://ncbi.nlm.nih.gov/pubmed/25523825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-014-0091-3
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