Leptin’s metabolic and immune functions can be uncoupled at the ligand/receptor interaction level

The adipocyte-derived cytokine leptin acts as a metabolic switch, connecting the body’s metabolism to high-energy consuming processes such as reproduction and immune responses. We here provide genetic and biochemical evidence that the metabolic and immune functions of leptin can be uncoupled at the...

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Detalhes bibliográficos
Publicado no:Cell Mol Life Sci
Main Authors: Zabeau, Lennart, Jensen, Cathy J., Seeuws, Sylvie, Venken, Koen, Verhee, Annick, Catteeuw, Dominiek, van Loo, Geert, Chen, Hui, Walder, Ken, Hollis, Jacob, Foote, Simon, Morris, Margaret J., Van der Heyden, José, Peelman, Frank, Oldfield, Brian J., Rubio, Justin P., Elewaut, Dirk, Tavernier, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Basel 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4293488/
https://ncbi.nlm.nih.gov/pubmed/25098352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-014-1697-x
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