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The effects of a humanized recombinant anti-cocaine monoclonal antibody on the disposition of cocaethylene in mice
The chimeric human/mouse anti-cocaine monoclonal antibody (mAb) 2E2 and its further humanized variant h2E2 have been reported to sequester a significant portion of cocaine in plasma and decrease cocaine concentrations in the brain in mice and rats. However, many cocaine users co-abuse alcohol, leadi...
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| Veröffentlicht in: | Int Immunopharmacol |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4293271/ https://ncbi.nlm.nih.gov/pubmed/25445957 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.intimp.2014.10.025 |
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