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The effects of a humanized recombinant anti-cocaine monoclonal antibody on the disposition of cocaethylene in mice

The chimeric human/mouse anti-cocaine monoclonal antibody (mAb) 2E2 and its further humanized variant h2E2 have been reported to sequester a significant portion of cocaine in plasma and decrease cocaine concentrations in the brain in mice and rats. However, many cocaine users co-abuse alcohol, leadi...

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Bibliografski detalji
Izdano u:Int Immunopharmacol
Glavni autori: Wetzel, Hanna N., Tabet, Michael R., Ball, William J., Norman, Andrew B.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4293271/
https://ncbi.nlm.nih.gov/pubmed/25445957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.intimp.2014.10.025
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