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Intestinal MUC2 mucin supramolecular topology by packing and release resting on D3 domain assembly
MUC2 is the major gel-forming mucin of the colon forming a protective gel barrier organized into an inner stratified and an outer loose layer. The MUC2 N-terminus (D1-D2-D'D3 domains) has a dual function in building a net-like structure by disulfide-bonded trimerization and packing the MUC2 pol...
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| Publicado no: | J Mol Biol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4293034/ https://ncbi.nlm.nih.gov/pubmed/24816392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2014.04.027 |
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