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Analgesic synergy between opioid and α(2)-adrenoceptors

Opioid and α(2)-adrenoceptor agonists are potent analgesic drugs and their analgesic effects can synergize when co-administered. These supra-additive interactions are potentially beneficial clinically; by increasing efficacy and/or reducing the total drug required to produce sufficient pain relief,...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Chabot-Doré, A-J, Schuster, D J, Stone, L S, Wilcox, G L
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292955/
https://ncbi.nlm.nih.gov/pubmed/24641506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12695
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