Interleukin-1β causes excitotoxic neurodegeneration and multiple sclerosis disease progression by activating the apoptotic protein p53

BACKGROUND: Understanding how inflammation causes neuronal damage is of paramount importance in multiple sclerosis (MS) and in other neurodegenerative diseases. Here we addressed the role of the apoptotic cascade in the synaptic abnormalities and neuronal loss caused by the proinflammatory cytokines...

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Dades bibliogràfiques
Publicat a:Mol Neurodegener
Autors principals: Rossi, Silvia, Motta, Caterina, Studer, Valeria, Macchiarulo, Giulia, Volpe, Elisabetta, Barbieri, Francesca, Ruocco, Gabriella, Buttari, Fabio, Finardi, Annamaria, Mancino, Raffaele, Weiss, Sagit, Battistini, Luca, Martino, Gianvito, Furlan, Roberto, Drulovic, Jelena, Centonze, Diego
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292815/
https://ncbi.nlm.nih.gov/pubmed/25495224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-9-56
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