Assessment of patient-derived tumour xenografts (PDXs) as a discovery tool for cancer epigenomics

BACKGROUND: The use of tumour xenografts is a well-established research tool in cancer genomics but has not yet been comprehensively evaluated for cancer epigenomics. METHODS: In this study, we assessed the suitability of patient-derived tumour xenografts (PDXs) for methylome analysis using Infinium...

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Vydáno v:Genome Med
Hlavní autoři: Guilhamon, Paul, Butcher, Lee M, Presneau, Nadege, Wilson, Gareth A, Feber, Andrew, Paul, Dirk S, Schütte, Moritz, Haybaeck, Johannes, Keilholz, Ulrich, Hoffman, Jens, Ross, Mark T, Flanagan, Adrienne M, Beck, Stephan
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292812/
https://ncbi.nlm.nih.gov/pubmed/25587359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-014-0116-0
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