Contribution of non-reference alleles in mtDNA of Alzheimer's disease patients

Many observations suggest that mutations of mitochondrial DNA (mtDNA) could be responsible for the neurodegenerative changes of Alzheimer's disease (AD). Here we examined the signal intensity of the four alleles of each mtDNA nucleotide position (np) in whole blood of AD patients and age-matche...

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Bibliographische Detailangaben
Veröffentlicht in:Ann Clin Transl Neurol
Hauptverfasser: Casoli, Tiziana, Di Stefano, Giuseppina, Spazzafumo, Liana, Balietti, Marta, Giorgetti, Belinda, Giuli, Cinzia, Postacchini, Demetrio, Fattoretti, Patrizia, Conti, Fiorenzo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd 2014
Schlagworte:
Brief Communications
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292745/
https://ncbi.nlm.nih.gov/pubmed/25590040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.42
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