Contribution of non-reference alleles in mtDNA of Alzheimer's disease patients

Many observations suggest that mutations of mitochondrial DNA (mtDNA) could be responsible for the neurodegenerative changes of Alzheimer's disease (AD). Here we examined the signal intensity of the four alleles of each mtDNA nucleotide position (np) in whole blood of AD patients and age-matche...

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Bibliografiske detaljer
Udgivet i:Ann Clin Transl Neurol
Main Authors: Casoli, Tiziana, Di Stefano, Giuseppina, Spazzafumo, Liana, Balietti, Marta, Giorgetti, Belinda, Giuli, Cinzia, Postacchini, Demetrio, Fattoretti, Patrizia, Conti, Fiorenzo
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2014
Fag:
Brief Communications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292745/
https://ncbi.nlm.nih.gov/pubmed/25590040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.42
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