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Induction of immunogenic cell death by targeting RIG-I-like helicases in pancreatic cancer
RIG-I-like helicases (RLH) are cytosolic sensors for viral RNA inducing type I interferon production. We found that pancreatic cancer cells express functional RLH and are susceptible to RLH-induced apoptosis via intrinsic and extrinsic pathways. Tumor cells displayed features of immunogenic cell dea...
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| Опубликовано в: : | Oncoimmunology |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Taylor & Francis
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4292725/ https://ncbi.nlm.nih.gov/pubmed/25941620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21624011.2014.955687 |
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