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Induction of immunogenic cell death by targeting RIG-I-like helicases in pancreatic cancer

RIG-I-like helicases (RLH) are cytosolic sensors for viral RNA inducing type I interferon production. We found that pancreatic cancer cells express functional RLH and are susceptible to RLH-induced apoptosis via intrinsic and extrinsic pathways. Tumor cells displayed features of immunogenic cell dea...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oncoimmunology
Egile Nagusiak: Schnurr, Max, Duewell, Peter
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292725/
https://ncbi.nlm.nih.gov/pubmed/25941620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21624011.2014.955687
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