Effects of Renal Failure and Dialysis on Cefazolin Pharmacokinetics

Serum and urinary levels of cefazolin were determined after a 500-mg parenteral dose in eight azotemic volunteers. The mean peak serum concentration was 1.5 to 5 times the levels obtained in nonazotemic patients. The serum half-life of cefazolin was increased significantly. In patients on dialysis,...

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Hlavní autoři: Madhavan, T., Yaremchuk, Kathy, Levin, Nathan, Fisher, Evelyn, Cox, Frank, Burch, Keith, Haas, Erwin, Pohlod, Don, Quinn, Edward L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 1975
Témata:
Pharmacology and Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC429262/
https://ncbi.nlm.nih.gov/pubmed/1164008
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