Effects of Renal Failure and Dialysis on Cefazolin Pharmacokinetics
Serum and urinary levels of cefazolin were determined after a 500-mg parenteral dose in eight azotemic volunteers. The mean peak serum concentration was 1.5 to 5 times the levels obtained in nonazotemic patients. The serum half-life of cefazolin was increased significantly. In patients on dialysis,...
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| Publicado no: | Antimicrob Agents Chemother |
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| Principais autores: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
1975
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC429262/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1164008/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.8.1.63 |
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