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Effects of Renal Failure and Dialysis on Cefazolin Pharmacokinetics

Serum and urinary levels of cefazolin were determined after a 500-mg parenteral dose in eight azotemic volunteers. The mean peak serum concentration was 1.5 to 5 times the levels obtained in nonazotemic patients. The serum half-life of cefazolin was increased significantly. In patients on dialysis,...

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Detaylı Bibliyografya
Yayımlandı:Antimicrob Agents Chemother
Asıl Yazarlar: Madhavan, T., Yaremchuk, Kathy, Levin, Nathan, Fisher, Evelyn, Cox, Frank, Burch, Keith, Haas, Erwin, Pohlod, Don, Quinn, Edward L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 1975
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC429262/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1164008/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.8.1.63
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