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Use of an Endogenous Plasmid Locus for Stable in trans Complementation in Borrelia burgdorferi

Targeted mutagenesis and complementation are important tools for studying genes of unknown function in the Lyme disease spirochete Borrelia burgdorferi. A standard method of complementation is reintroduction of a wild-type copy of the targeted gene on a shuttle vector. However, shuttle vectors are p...

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Bibliografiska uppgifter
I publikationen:Appl Environ Microbiol
Huvudupphovsmän: Kasumba, Irene N., Bestor, Aaron, Tilly, Kit, Rosa, Patricia A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292500/
https://ncbi.nlm.nih.gov/pubmed/25452278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.03657-14
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