The Role of Notch in the Cardiovascular System: Potential Adverse Effects of Investigational Notch Inhibitors

Targeting the Notch pathway is a new promising therapeutic approach for cancer patients. Inhibition of Notch is effective in the oncology setting because it causes a reduction of highly proliferative tumor cells and it inhibits survival of cancer stem cells, which are considered responsible for tumo...

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Detalhes bibliográficos
Publicado no:Front Oncol
Principais autores: Rizzo, Paola, Mele, Donato, Caliceti, Cristiana, Pannella, Micaela, Fortini, Cinzia, Clementz, Anthony George, Morelli, Marco Bruno, Aquila, Giorgio, Ameri, Pietro, Ferrari, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292456/
https://ncbi.nlm.nih.gov/pubmed/25629006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2014.00384
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