17β-estradiol enhances signalling mediated by VEGF-A-delta-like ligand 4-notch1 axis in human endothelial cells.

Estrogens play a protective role in coronary artery disease. The mechanisms of action are still poorly understood, although a role for estrogens in stimulation of angiogenesis has been suggested. In several cell types, estrogens modulate the Notch pathway, which is involved in controlling angiogenes...

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Main Authors: Cristiana Caliceti, Giorgio Aquila, Micaela Pannella, Marco Bruno Morelli, Cinzia Fortini, Paolo Pinton, Massimo Bonora, Silvana Hrelia, Antonio Pannuti, Lucio Miele, Paola Rizzo, Roberto Ferrari
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2013-01-01
Serier:PLoS ONE
Online adgang:http://europepmc.org/articles/PMC3742772?pdf=render
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