In situ loading of skin dendritic cells with apoptotic bleb-derived antigens for the induction of tumor-directed immunity

The generation and loading of dendritic cells (DC) ex-vivo for tumor vaccination purposes is laborious and costly. Direct intradermal (i.d.) administration of tumor-associated antigens could be an attractive alternative approach, provided that efficient uptake and cross-presentation by appropriately...

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Bibliographic Details
Published in:Oncoimmunology
Main Authors: Ruben, Jurjen M, Bontkes, Hetty J, Westers, Theresia M, Hooijberg, Erik, Ossenkoppele, Gert J, van de Loosdrecht, Arjan A, de Gruijl, Tanja D
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2014
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292219/
https://ncbi.nlm.nih.gov/pubmed/25610730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21624011.2014.946360
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