Differential capacity of human interleukin-4 and interferon-α monocyte-derived dendritic cells for cross-presentation of free versus cell-associated antigen

Dendritic cells (DC) vaccination is a potent therapeutic approach for inducing tumor-directed immunity, but challenges remain. One of the particular interest is the induction of an immune response targeting multiple (unknown) tumor-associated antigens (TAA), which requires a polyvalent source of TAA...

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Publicado en:Cancer Immunol Immunother
Autores principales: Ruben, Jurjen M., Bontkes, Hetty J., Westers, Theresia M., Hooijberg, Erik, Ossenkoppele, Gert J., de Gruijl, Tanja D., van de Loosdrecht, Arjan A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer Berlin Heidelberg 2015
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4612333/
https://ncbi.nlm.nih.gov/pubmed/26216454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-015-1741-1
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