Priming of PRAME- and WT1-specific CD8(+) T cells in healthy donors but not in AML patients in complete remission: Implications for immunotherapy

Active immunotherapy may prevent the relapse of acute myeloid leukemia (AML) by inducing leukemia-specific T cells. Here, we investigated whether Wilms’ tumor 1 (WT1) and preferentially expressed antigen in melanoma (PRAME)-specific T cells could be induced upon the priming of healthy donor- and AML...

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Detalhes bibliográficos
Main Authors: van den Ancker, Willemijn, Ruben, Jurjen M., Westers, Theresia M., Wulandari, Dewi, Bontkes, Hetty J., Hooijberg, Erik, Stam, Anita G.M., Santegoets, Saskia J.A.M., Ossenkoppele, Gert J., de Gruijl, Tanja, van de Loosdrecht, Arjan
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Brief Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3654602/
https://ncbi.nlm.nih.gov/pubmed/23734332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.23971
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