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Relating Toxicity to Transfection: Using Sphingosine To Maintain Prolonged Expression in Vitro

[Image: see text] Cationic reagents are commonly used to facilitate DNA delivery, and transfection experiments are typically initiated in cell culture where the optimal charge ratio is determined. While transfection rates are often enhanced at higher +/– charge ratios, the cellular toxicity associat...

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Publicat a:Mol Pharm
Autors principals: Betker, Jamie L., Anchordoquy, Thomas J.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2014
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291780/
https://ncbi.nlm.nih.gov/pubmed/25418523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp500604r
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