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Bioorthogonal Tetrazine-Mediated Transfer Reactions Facilitate Reaction Turnover in Nucleic Acid-Templated Detection of MicroRNA

[Image: see text] Tetrazine ligations have proven to be a powerful bioorthogonal technique for the detection of many labeled biomolecules, but the ligating nature of these reactions can limit reaction turnover in templated chemistry. We have developed a transfer reaction between 7-azabenzonorbornadi...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Wu, Haoxing, Cisneros, Brandon T., Cole, Christian M., Devaraj, Neal K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291768/
https://ncbi.nlm.nih.gov/pubmed/25495860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja510839r
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