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(68)Ga chelating bioorthogonal tetrazine polymers for the multistep labeling of cancer biomarkers

We have developed a (68)Ga metal chelating bioorthogonal tetrazine dextran probe that is highly reactive with trans-cyclooctene modified monoclonal antibodies for multistep imaging applications. Confocal microscopy and positron emission tomography (PET) were used to characterize the dextran probe in...

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Autors principals: Nichols, Brandon, Qin, Zhengtao, Yang, Jun, Vera, David R., Devaraj, Neal K.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4119763/
https://ncbi.nlm.nih.gov/pubmed/24589653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3cc49530b
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