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Superresolution microscopy reveals spatial separation of UCP4 and F(0)F(1)-ATP synthase in neuronal mitochondria

Because different proteins compete for the proton gradient across the inner mitochondrial membrane, an efficient mechanism is required for allocation of associated chemical potential to the distinct demands, such as ATP production, thermogenesis, regulation of reactive oxygen species (ROS), etc. Her...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Klotzsch, Enrico, Smorodchenko, Alina, Löfler, Lukas, Moldzio, Rudolf, Parkinson, Elena, Schütz, Gerhard J., Pohl, Elena E.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291679/
https://ncbi.nlm.nih.gov/pubmed/25535394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1415261112
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