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Superresolution microscopy reveals spatial separation of UCP4 and F(0)F(1)-ATP synthase in neuronal mitochondria

Because different proteins compete for the proton gradient across the inner mitochondrial membrane, an efficient mechanism is required for allocation of associated chemical potential to the distinct demands, such as ATP production, thermogenesis, regulation of reactive oxygen species (ROS), etc. Her...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Klotzsch, Enrico, Smorodchenko, Alina, Löfler, Lukas, Moldzio, Rudolf, Parkinson, Elena, Schütz, Gerhard J., Pohl, Elena E.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291679/
https://ncbi.nlm.nih.gov/pubmed/25535394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1415261112
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