Transdermal deferoxamine prevents pressure-induced diabetic ulcers

There is a high mortality in patients with diabetes and severe pressure ulcers. For example, chronic pressure sores of the heels often lead to limb loss in diabetic patients. A major factor underlying this is reduced neovascularization caused by impaired activity of the transcription factor hypoxia...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Duscher, Dominik, Neofytou, Evgenios, Wong, Victor W., Maan, Zeshaan N., Rennert, Robert C., Inayathullah, Mohammed, Januszyk, Michael, Rodrigues, Melanie, Malkovskiy, Andrey V., Whitmore, Arnetha J., Walmsley, Graham G., Galvez, Michael G., Whittam, Alexander J., Brownlee, Michael, Rajadas, Jayakumar, Gurtner, Geoffrey C.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2015
Teme:
Biological Sciences
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291638/
https://ncbi.nlm.nih.gov/pubmed/25535360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1413445112
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