Transdermal deferoxamine prevents pressure-induced diabetic ulcers

There is a high mortality in patients with diabetes and severe pressure ulcers. For example, chronic pressure sores of the heels often lead to limb loss in diabetic patients. A major factor underlying this is reduced neovascularization caused by impaired activity of the transcription factor hypoxia...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Duscher, Dominik, Neofytou, Evgenios, Wong, Victor W., Maan, Zeshaan N., Rennert, Robert C., Inayathullah, Mohammed, Januszyk, Michael, Rodrigues, Melanie, Malkovskiy, Andrey V., Whitmore, Arnetha J., Walmsley, Graham G., Galvez, Michael G., Whittam, Alexander J., Brownlee, Michael, Rajadas, Jayakumar, Gurtner, Geoffrey C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291638/
https://ncbi.nlm.nih.gov/pubmed/25535360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1413445112
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