Transdermal deferoxamine prevents pressure-induced diabetic ulcers

There is a high mortality in patients with diabetes and severe pressure ulcers. For example, chronic pressure sores of the heels often lead to limb loss in diabetic patients. A major factor underlying this is reduced neovascularization caused by impaired activity of the transcription factor hypoxia...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Duscher, Dominik, Neofytou, Evgenios, Wong, Victor W., Maan, Zeshaan N., Rennert, Robert C., Inayathullah, Mohammed, Januszyk, Michael, Rodrigues, Melanie, Malkovskiy, Andrey V., Whitmore, Arnetha J., Walmsley, Graham G., Galvez, Michael G., Whittam, Alexander J., Brownlee, Michael, Rajadas, Jayakumar, Gurtner, Geoffrey C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2015
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291638/
https://ncbi.nlm.nih.gov/pubmed/25535360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1413445112
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