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Human 3D vascularized organotypic microfluidic assays to study breast cancer cell extravasation

A key aspect of cancer metastases is the tendency for specific cancer cells to home to defined subsets of secondary organs. Despite these known tendencies, the underlying mechanisms remain poorly understood. Here we develop a microfluidic 3D in vitro model to analyze organ-specific human breast canc...

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Podrobná bibliografie
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Jeon, Jessie S., Bersini, Simone, Gilardi, Mara, Dubini, Gabriele, Charest, Joseph L., Moretti, Matteo, Kamm, Roger D.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291627/
https://ncbi.nlm.nih.gov/pubmed/25524628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1417115112
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