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Human 3D vascularized organotypic microfluidic assays to study breast cancer cell extravasation
A key aspect of cancer metastases is the tendency for specific cancer cells to home to defined subsets of secondary organs. Despite these known tendencies, the underlying mechanisms remain poorly understood. Here we develop a microfluidic 3D in vitro model to analyze organ-specific human breast canc...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4291627/ https://ncbi.nlm.nih.gov/pubmed/25524628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1417115112 |
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