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Hexokinase II integrates energy metabolism and cellular protection: Akting on mitochondria and TORCing to autophagy

Accumulating evidence reveals that metabolic and cell survival pathways are closely related, sharing common signaling molecules. Hexokinase catalyzes the phosphorylation of glucose, the rate-limiting first step of glycolysis. Hexokinase II (HK-II) is a predominant isoform in insulin-sensitive tissue...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Roberts, D J, Miyamoto, S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291497/
https://ncbi.nlm.nih.gov/pubmed/25323588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.173
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