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Too sweet for autophagy: hexokinase inhibition of mTORC1 activates autophagy
In this issue, Roberts et al. (2014) describe how hexokinase and mTORC1 cooperate to sense disequilibrium between glucose uptake and utilization and direct the balance of anabolism and catabolism to ensure the appropriate use of cellular resources.
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4106709/ https://ncbi.nlm.nih.gov/pubmed/24560270 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.02.009 |
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