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The Investigational Agent E1210 Is Effective in Treatment of Experimental Invasive Candidiasis Caused by Resistant Candida albicans

The in vitro and in vivo activity of the inositol acyltransferase inhibitor E1210 was evaluated against echinocandin-resistant Candida albicans. E1210 demonstrated potent in vitro activity, and in mice with invasive candidiasis caused by echinocandin-resistant C. albicans, oral doses of 10 and 40 mg...

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書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Wiederhold, Nathan P., Najvar, Laura K., Fothergill, Annette W., McCarthy, Dora I., Bocanegra, Rosie, Olivo, Marcos, Kirkpatrick, William R., Everson, Michael P., Duncanson, Frederick P., Patterson, Thomas F.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291422/
https://ncbi.nlm.nih.gov/pubmed/25331706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03944-14
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