Pharmacokinetics and safety of rifabutin in young HIV-infected children receiving rifabutin and lopinavir/ritonavir

OBJECTIVES: Co-treatment of HIV and TB in young children is complicated by limited treatment options and complex drug–drug interactions. Rifabutin is an alternative to rifampicin for adults receiving a ritonavir-boosted PI. We aimed to evaluate the short-term safety and pharmacokinetics of rifabutin...

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Vydáno v:J Antimicrob Chemother
Hlavní autoři: Moultrie, Harry, McIlleron, Helen, Sawry, Shobna, Kellermann, Tracy, Wiesner, Lubbe, Kindra, Gurpreet, Gous, Hermien, Van Rie, Annelies
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2015
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291235/
https://ncbi.nlm.nih.gov/pubmed/25281400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dku382
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