Rifabutin pharmacokinetics and safety among TB/HIV-coinfected children receiving lopinavir/ritonavir-containing second-line ART

BACKGROUND: Treatment options are limited for TB/HIV-coinfected children who require PI-based ART. Rifabutin is the preferred rifamycin for adults on PIs, but the one study evaluating rifabutin with PIs among children was stopped early due to severe neutropenia. METHODS: We evaluated rifabutin safet...

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Detalhes bibliográficos
Publicado no:J Antimicrob Chemother
Main Authors: Rawizza, Holly E, Oladokun, Regina, Ejeliogu, Emeka, Oguche, Stephen, Ogunbosi, Babatunde O, Agbaji, Oche, Odaibo, Georgina, Imade, Godwin, Olaleye, David, Wiesner, Lubbe, Darin, Kristin M, Okonkwo, Prosper, Kanki, Phyllis J, Scarsi, Kimberly K, McIlleron, Helen M
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7879135/
https://ncbi.nlm.nih.gov/pubmed/33294914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkaa512
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