Rifabutin pharmacokinetics and safety among TB/HIV-coinfected children receiving lopinavir/ritonavir-containing second-line ART

BACKGROUND: Treatment options are limited for TB/HIV-coinfected children who require PI-based ART. Rifabutin is the preferred rifamycin for adults on PIs, but the one study evaluating rifabutin with PIs among children was stopped early due to severe neutropenia. METHODS: We evaluated rifabutin safet...

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Dades bibliogràfiques
Publicat a:J Antimicrob Chemother
Autors principals: Rawizza, Holly E, Oladokun, Regina, Ejeliogu, Emeka, Oguche, Stephen, Ogunbosi, Babatunde O, Agbaji, Oche, Odaibo, Georgina, Imade, Godwin, Olaleye, David, Wiesner, Lubbe, Darin, Kristin M, Okonkwo, Prosper, Kanki, Phyllis J, Scarsi, Kimberly K, McIlleron, Helen M
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7879135/
https://ncbi.nlm.nih.gov/pubmed/33294914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkaa512
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