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Electron Microscopy in Rat Brain Slices Reveals Rapid Accumulation of Cisplatin on Ribosomes and Other Cellular Components Only in Glia

Cisplatin is a widely used, effective anticancer drug. Its use, however, is associated with several side effects including nephrotoxicity and neurotoxicity. It is known that cisplatin is accumulated in cells by the organic cation transport system and reacts with nucleotides, damaging them, but the p...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Chemother Res Pract
Egile Nagusiak: Zueva, Lidia, Rivera, Yomarie, Kucheryavykh, Lilia, Skatchkov, Serguei N., Eaton, Misty J., Sanabria, Priscila, Inyushin, Mikhail
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Hindawi Publishing Corporation 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291194/
https://ncbi.nlm.nih.gov/pubmed/25610648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/174039
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