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Glioblastoma development in mouse brain: general reduction of OCTs and mislocalization of OCT3 transporter and subsequent uptake of ASP(+) substrate to the nuclei

Organic cation transporters (OCTs) were first found and then isolated from cultured glioma cells. When glioma cells are implanted into brain the fate of OCTs varies with time after implantation and transporter type. Here we report that OCT1, OCT2 and OCT3 immunofluorescence is significantly reduced...

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Detalhes bibliográficos
Main Authors: Kucheryavykh, Lilia Y, Rolón-Reyes, Kimberleve, Kucheryavykh, Yuriy V, Skatchkov, Serguei, Eaton, Misty J., Sanabria, Priscila, Wessinger, William D., Inyushin, Mikhail
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143131/
https://ncbi.nlm.nih.gov/pubmed/25165637
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