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Glioblastoma development in mouse brain: general reduction of OCTs and mislocalization of OCT3 transporter and subsequent uptake of ASP(+) substrate to the nuclei

Organic cation transporters (OCTs) were first found and then isolated from cultured glioma cells. When glioma cells are implanted into brain the fate of OCTs varies with time after implantation and transporter type. Here we report that OCT1, OCT2 and OCT3 immunofluorescence is significantly reduced...

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Autors principals: Kucheryavykh, Lilia Y, Rolón-Reyes, Kimberleve, Kucheryavykh, Yuriy V, Skatchkov, Serguei, Eaton, Misty J., Sanabria, Priscila, Wessinger, William D., Inyushin, Mikhail
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143131/
https://ncbi.nlm.nih.gov/pubmed/25165637
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