BRAF Inhibitor Dabrafenib in Patients with Metastatic BRAF-Mutant Thyroid Cancer

Background: Mutations of v-raf murine sarcoma viral oncogene homolog B (BRAF) are commonly identified in papillary and anaplastic thyroid carcinoma and are associated with worse prognosis compared with the wild type. BRAF inhibition in papillary thyroid carcinoma cell lines and xenografts inhibits p...

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Bibliografske podrobnosti
izdano v:Thyroid
Main Authors: Falchook, Gerald S., Millward, Michael, Hong, David, Naing, Aung, Piha-Paul, Sarina, Waguespack, Steven G., Cabanillas, Maria E., Sherman, Steven I., Ma, Bo, Curtis, Martin, Goodman, Vicki, Kurzrock, Razelle
Format: Artigo
Jezik:Inglês
Izdano: Mary Ann Liebert, Inc. 2015
Teme:
Thyroid Cancer and Nodules
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291160/
https://ncbi.nlm.nih.gov/pubmed/25285888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2014.0123
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