BRAF Inhibitor Dabrafenib in Patients with Metastatic BRAF-Mutant Thyroid Cancer

Background: Mutations of v-raf murine sarcoma viral oncogene homolog B (BRAF) are commonly identified in papillary and anaplastic thyroid carcinoma and are associated with worse prognosis compared with the wild type. BRAF inhibition in papillary thyroid carcinoma cell lines and xenografts inhibits p...

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Detalhes bibliográficos
Publicado no:Thyroid
Main Authors: Falchook, Gerald S., Millward, Michael, Hong, David, Naing, Aung, Piha-Paul, Sarina, Waguespack, Steven G., Cabanillas, Maria E., Sherman, Steven I., Ma, Bo, Curtis, Martin, Goodman, Vicki, Kurzrock, Razelle
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2015
Assuntos:
Thyroid Cancer and Nodules
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291160/
https://ncbi.nlm.nih.gov/pubmed/25285888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2014.0123
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