BRAF Inhibitor Dabrafenib in Patients with Metastatic BRAF-Mutant Thyroid Cancer

Background: Mutations of v-raf murine sarcoma viral oncogene homolog B (BRAF) are commonly identified in papillary and anaplastic thyroid carcinoma and are associated with worse prognosis compared with the wild type. BRAF inhibition in papillary thyroid carcinoma cell lines and xenografts inhibits p...

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Detaylı Bibliyografya
Yayımlandı:Thyroid
Asıl Yazarlar: Falchook, Gerald S., Millward, Michael, Hong, David, Naing, Aung, Piha-Paul, Sarina, Waguespack, Steven G., Cabanillas, Maria E., Sherman, Steven I., Ma, Bo, Curtis, Martin, Goodman, Vicki, Kurzrock, Razelle
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Mary Ann Liebert, Inc. 2015
Konular:
Thyroid Cancer and Nodules
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291160/
https://ncbi.nlm.nih.gov/pubmed/25285888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2014.0123
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