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Membrane Shape at the Edge of the Dynamin Helix Sets Location and Duration of the Fission Reaction

The GTPase dynamin polymerizes into a helical coat that constricts membrane necks of endocytic pits to promote their fission. However, the dynamin mechanism is still debated because constriction is necessary but not sufficient for fission. Here, we show that fission occurs at the interface between t...

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發表在:Cell
Main Authors: Morlot, Sandrine, Galli, Valentina, Klein, Marius, Chiaruttini, Nicolas, Manzi, John, Humbert, Frédéric, Dinis, Luis, Lenz, Martin, Cappello, Giovanni, Roux, Aurélien
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4290832/
https://ncbi.nlm.nih.gov/pubmed/23101629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.09.017
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