Membrane Shape at the Edge of the Dynamin Helix Sets Location and Duration of the Fission Reaction

The GTPase dynamin polymerizes into a helical coat that constricts membrane necks of endocytic pits to promote their fission. However, the dynamin mechanism is still debated because constriction is necessary but not sufficient for fission. Here, we show that fission occurs at the interface between t...

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Pubblicato in:Cell
Autori principali: Morlot, Sandrine, Galli, Valentina, Klein, Marius, Chiaruttini, Nicolas, Manzi, John, Humbert, Frédéric, Dinis, Luis, Lenz, Martin, Cappello, Giovanni, Roux, Aurélien
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4290832/
https://ncbi.nlm.nih.gov/pubmed/23101629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.09.017
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