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Dynamic remodeling of the dynamin helix during membrane constriction

Dynamin is a dimeric GTPase that assembles into a helix around the neck of endocytic buds. Upon GTP hydrolysis, dynamin breaks these necks, a reaction called membrane fission. Fission requires dynamin to first constrict the membrane. It is unclear, however, how dynamin helix constriction works. Here...

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Foilsithe in:Proc Natl Acad Sci U S A
Main Authors: Colom, Adai, Redondo-Morata, Lorena, Chiaruttini, Nicolas, Roux, Aurélien, Scheuring, Simon
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5448220/
https://ncbi.nlm.nih.gov/pubmed/28484031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1619578114
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