Relaxation of Loaded ESCRT-III Spiral Springs Drives Membrane Deformation

ESCRT-III is required for lipid membrane remodeling in many cellular processes, from abscission to viral budding and multi-vesicular body biogenesis. However, how ESCRT-III polymerization generates membrane curvature remains debated. Here, we show that Snf7, the main component of ESCRT-III, polymeri...

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Bibliografske podrobnosti
izdano v:Cell
Main Authors: Chiaruttini, Nicolas, Redondo-Morata, Lorena, Colom, Adai, Humbert, Frédéric, Lenz, Martin, Scheuring, Simon, Roux, Aurélien
Format: Artigo
Jezik:Inglês
Izdano: Cell Press 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4644223/
https://ncbi.nlm.nih.gov/pubmed/26522593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.10.017
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